UNFULFILLED AMBITION

18th May 13

(Source: butthorn, via erikuhhhlee)

17th May 13

(Source: curi-o-sity, via erikuhhhlee)

17th May 13

goodtypography:

caitlin burns

(via princerhaegars)

17th May 13

mishoverlord:

irrationalwitch:

pottercolours:

friendly reminder that when oliver wood addressed the gryffindor quidditch team as ‘men’, angelina johnson called him out on his sexist and misogynistic bullshit by reminding him there were women on the team too, and he listened to her without question ✿◕‿◕✿

#he’s a keeper

image

(via mypocketshurt90)

17th May 13
breeannabodybag666:

riahreah:

he meows so hard he falls over :o

omg i want them all.

breeannabodybag666:

riahreah:

he meows so hard he falls over :o

omg i want them all.

(Source: masterofthepotatos, via mypocketshurt90)

17th May 13
scinerds:

Scientists Report First Success in Cloning Human Stem Cells

It’s been 17 years since Dolly the sheep was cloned from a mammary cell. And now scientists applied the same technique to make the first embryonic stem cell lines from human skin cells.
Ever since Ian Wilmut, an unassuming embryologist working at the Roslin Institute just outside of Edinburgh stunned the world by cloning the first mammal, Dolly, scientists have been asking – could humans be cloned in the same way? Putting aside the ethical challenges the question raised, the query turned out to involve more wishful thinking than scientific success. Despite the fact that dozens of other species have been cloned using the technique, called nuclear transfer, human cells have remained stubbornly resistant to the process.
Until now. Shoukhrat Mitalipov, a professor at Oregon Health & Science University and his colleagues report in the journal Cell that they have successfully reprogrammed human skin cells back to their embryonic state. The purpose of the study, however, was not to generate human clones but to produce lines of embryonic stem cells. These can develop into muscle, nerve, or other cells that make up the body’s tissues. The process, he says, took only a few months, a surprisingly short period to reach such an important milestone.
Nuclear transfer involves inserting a fully developed cell – in Mitalipov’s study, the cells came from the skin of fetuses – into the nucleus of an egg, and then manipulating the egg to start dividing, a process that normally only occurs after it has been fertilized by a sperm. After several days, the ball of cells that results contains a blanket of embryonic stem cells endowed with the genetic material of the donor skin cell, which have the ability to generate every cell type from that donor. In Dolly’s case, those cells were allowed to continue developing into an embryo that was then transferred to a ewe to produce a cloned sheep. But Mitalipov says his process with the human cells isn’t designed to generate a human clone, but rather just to create the embryonic stem cells. These could then be manipulated to create heart, nerve or other cells that can repair or treat disease.
“I think this is a really important advance,” says Dieter Egli, an investigator at the New York Stem Cell Foundation. “I have a very high confidence that versions of this technique will work very well; it’s something that the field has been waiting for.” Egli is among the handful of scientists who have been working to perfect the technique with human cells and in 2011, succeeded in producing human stem cells, but with double the number of chromosomes. In 2004, Woo Suk Hwang, a veterinary scientist at Seoul National University, claimed to have succeeded in achieving the feat, but later admitted to faking the data. Instead of generating embryonic stem cell lines via nuclear transfer, Hwang’s group produced the stem cells from days-old embryos, a technique that had already been established by James Thomson at University of Wisconsin in 1998.

Full Article

scinerds:

Scientists Report First Success in Cloning Human Stem Cells

It’s been 17 years since Dolly the sheep was cloned from a mammary cell. And now scientists applied the same technique to make the first embryonic stem cell lines from human skin cells.

Ever since Ian Wilmut, an unassuming embryologist working at the Roslin Institute just outside of Edinburgh stunned the world by cloning the first mammal, Dolly, scientists have been asking – could humans be cloned in the same way? Putting aside the ethical challenges the question raised, the query turned out to involve more wishful thinking than scientific success. Despite the fact that dozens of other species have been cloned using the technique, called nuclear transfer, human cells have remained stubbornly resistant to the process.

Until now. Shoukhrat Mitalipov, a professor at Oregon Health & Science University and his colleagues report in the journal Cell that they have successfully reprogrammed human skin cells back to their embryonic state. The purpose of the study, however, was not to generate human clones but to produce lines of embryonic stem cells. These can develop into muscle, nerve, or other cells that make up the body’s tissues. The process, he says, took only a few months, a surprisingly short period to reach such an important milestone.

Nuclear transfer involves inserting a fully developed cell – in Mitalipov’s study, the cells came from the skin of fetuses – into the nucleus of an egg, and then manipulating the egg to start dividing, a process that normally only occurs after it has been fertilized by a sperm. After several days, the ball of cells that results contains a blanket of embryonic stem cells endowed with the genetic material of the donor skin cell, which have the ability to generate every cell type from that donor. In Dolly’s case, those cells were allowed to continue developing into an embryo that was then transferred to a ewe to produce a cloned sheep. But Mitalipov says his process with the human cells isn’t designed to generate a human clone, but rather just to create the embryonic stem cells. These could then be manipulated to create heart, nerve or other cells that can repair or treat disease.

“I think this is a really important advance,” says Dieter Egli, an investigator at the New York Stem Cell Foundation. “I have a very high confidence that versions of this technique will work very well; it’s something that the field has been waiting for.” Egli is among the handful of scientists who have been working to perfect the technique with human cells and in 2011, succeeded in producing human stem cells, but with double the number of chromosomes. In 2004, Woo Suk Hwang, a veterinary scientist at Seoul National University, claimed to have succeeded in achieving the feat, but later admitted to faking the data. Instead of generating embryonic stem cell lines via nuclear transfer, Hwang’s group produced the stem cells from days-old embryos, a technique that had already been established by James Thomson at University of Wisconsin in 1998.

Full Article

(via mypocketshurt90)

16th May 13
f-abulush:

i need this on my blog :>

f-abulush:

i need this on my blog :>

(Source: bliss-injection, via backtothree)

16th May 13

definitelydope:

Vienna by Lorenzo Morandi

(via backtothree)

16th May 13

insideonemind:

It’s hard to maintain that military composure when one’s granny is inspecting! 

I love how all the others are like ‘It’s the Queen I need to stand straighter and be more professional than I’ve ever been in my entire life’ and William and Harry are just like ‘lol hi Gran!’

FOREVER REBLOG

I like to think she tries to make them laugh. 

image

Reblogging because SHE’S ACTUALLY SMILING

Also Harry’s face.

this is still the best post on tumblr, forever.

Two very cute pictures.

(Source: princessdianafrances, via backtothree)

16th May 13

Interviewer: How do you see your characters evolving ?
Rupert: Well. Ron and Hermione are definitely friends now. But, it’s gonna change. They are definitely something else. They are soulmates. I think they end up together. But it’s a secret, don’t tell her I said that.

(via sansahardyngs)

15th May 13

rennyskywalker:

straightontilneverland:

#someone should troll the 50 Shades casting and do this

Oh my God I was going to reblog just for the gifs and THEN I saw the tag

(Source: freecocaine, via iflifegetsyoudown)

15th May 13
  • *Wakes up in the middle of the night*
  • Me: Please don't be 6am
  • *1;48am*
  • Me: MERRY FUCKING CHRISTMAS TO ME!
  • *Shoves face back into pillow*
15th May 13
kaonicks:

premiumgifs:

[video]

Oh! Look at this sweet baby :)

kaonicks:

premiumgifs:

[video]

Oh! Look at this sweet baby :)

(via raelovesasimplemelody)

15th May 13
tastefullyoffensive:

[via]

tastefullyoffensive:

[via]

(via mypocketshurt90)

14th May 13

eatingclean-gettinglean:

salvagingsarah:

Now that I know how to do this, I feel like I can do anything.

OH MY GOD THIS IS SO FUCKING SMART

(Source: pinkricee, via iflifegetsyoudown)